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Rx Pad

Improving the Health of Your Clinical Practice
Mar
06

Mechanisms of Action of Hyperbaric Oxygen Therapy in Carbon Monoxide Poisoning

Mechanisms of Action of HBO2 in Carbon Monoxide Poisoning

Current knowledge indicates that there are multiple mechanisms of action of hyperbaric oxygen therapy in CO poisoning. Based on the law of mass action, elevated partial pressures of O2 will accelerate the rate of CO dissociation from hemoglobin. Thus, COHb half-life can be decreased from approximately 5 .5 hours when breathing air and to approximately 20 minutes when breathing O2 at 3 ATA. Indeed, this was the reasoning behind the first clinical implementation of hyperbaric oxygen therapy for CO poisoning. As the COHb level is not associated with clinical risk, it is hard to accept that a more rapid dissociation of CO from hemoglobin could be the central factor for the benefit of hyperbaric oxygen . A fraction of the acute mortality from CO is due to hypoxia, however, and prompt removal of CO from hemoglobin will be of benefit . HBO2 also promotes normalization of tissue hypoxia. CO binds to cytochrome oxidase, particularly when the COHb level exceeds 40% to 50% . Brown and Piantadosi demonstrated that hyperbaric oxygen at 3 ATA markedly accelerates the dissociation of CO from cytochrome oxidase. Furthermore, it was shown that HBO2 completely reversed brain mitochondrial electron transport chain inhibition by CO. Hyperbaric oxygen also has effects related to the cascade of vascular injury triggered by CO poisoning. Hyperbaric oxygen was found to be effective for preventing brain oxidative injury through increased heme oxygenase and upregulation of antioxidants. The mechanism appears to be associated with denaturation of a membrane-associated guanylate cyclase that plays a role in coordinating the elevated affinity of beta 2 integrins expressed on the cell surface. Given that vascular changes are prominent in clinical CO poisoning, it is feasible that neurological sequelae in patients may involve a perivascular injury mediated by leukocyte sequestration and activation. Moreover, HBO2 reduces neuronal apoptosis and necrosis, and it also mobilizes stem cells via a nitric oxide–dependent mechanism. Hence, timely administration of hyperbaric oxygen may ameliorate the cascade leading to brain injury via multiple mechanisms.

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Nov
23

Black Friday Sale Is Open! (save on all wound care courses)

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If you've been thinking of taking a training course to become certified in wound care (or need a refresher) - now is a great time to take action!

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May
28

2 Aspects that Influence Hyperbaric Safety

2 Aspects That Influence Hyperbaric Safety Learn Hyperbaric Facility Safety

There are two distinct aspects to the field of hyperbaric medicine that influence safety: 

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May
19

How to become certified in hyperbaric medicine

How-to-become-certified-in-Hyperbaric Medicine How to become certified in hyperbaric medicine.

 

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May
18

COVID-19 Information

COVID-19 Information as related to wound care and hyperbaric medicine COVID-19 Information as related to wound care and hyperbaric medicine

We have aggregrated information and resources for you that answer many questions and offer the latest knowledge, research, and treaments of COVID-19 as related to wound care and hyperbaric medicine.

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May
08

Do I need to be a certified EMT to take the CHT classes?

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Question: I am interested in the CHT classes. Can you guide me as to what I need? I just finished an EMT course. Do I need to be certified EMT to take the CHT classes?

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Mar
24

Nationally Approved Livestream Courses Are Now Available for Wound Care and Hyperbaric Medicine Training

COVID-19 Plan To Continue Your Training in Hyperbaric Medicine and Wound Care

First, a huge and heartfelt thank you to all providers who have been called into action on the front lines of the COVID-19 response. Thank you. 

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Jun
04

Gas Gangrene: Antibiotics vs. HBO2

Although the incidence of clostridial myonecrosis infections has dropped precipitously in recent decades, it always remains a threat in injuries where contamination and severe tissue disruption have occurred.

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Mar
26

Video Lesson: The Explosion of Chronic Wounds in the U.S.

This short video lesson taught by Dr. Michael White, MD, UHM, MMM, CWS discusses the explosion of chronic wounds within the U.S. and the opportunity for wound care and hyperbaric medicine clinics to serve more patients.

Click the image below to watch the video lesson

Screen Shot 2019 03 26 at 11.26.52 AM

Or use the following link to watch the video https://youtu.be/4H1rXuKZEEo

 

Learn more at the 2-day workshop hosted by Wound Care Education Partners, The Business of Wound Care and Hyperbaric Medicine

Find all details and registration information here https://woundeducationpartners.com/live-courses/upcoming-courses/the-business-of-wound-care-and-hyperbaric-medicine/300-the-business-of-wound-care-and-hyperbaric-medicine-planning-your-clinic-s-long-term-success-north-palm-beach-fl.html

Accreditation Statement: The Undersea and Hyperbaric Medical Society designates this live activity for a maximum of 16 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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Mar
20

Are there prerequisites for taking the CHT course?

We often get the question, "Are there pre-requisites for taking the CHT course?"

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Oct
09

5 questions to help you plan your CME/CEU credits for next year

"Before anything else, preparation is the key to success." - Alexandar Graham Bell

It's time to start planning now to earn your 2019 CME/CNE/CEU credits. Don't know how to start? Below are five questions to help you start the planning process, and watch the short video to get all the details.

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Copyright

© Wound Care Education Partners. All Rights Reserved.

Oct
16

Job Opening in Delaware - Physician - Wound Care - Full-time

PHYSICIAN - WOUND CARE (FT)

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Sep
19

Think In Ink – What to Document for Medical Necessity

 

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Sep
11

4 Easy Steps to Market Your Clinic

By providing community education to potential patients you are building awareness, and with that awareness we’re able to impact healing outcomes for patients in our community.

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© Wound Care Education Partners. All Rights Reserved.

Sep
10

How Key Are Front Office Operations To The Wound Clinic Business?

Have you thought about the impact of the front office operations in the success, health, and growth of your wound care and hyperbaric medicine clinic?

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© Wound Care Education Partners. All Rights Reserved.

Aug
29

Wound Dressing Selection

Question: Patients present to the wound care practitioner in a myriad of ways, how does the practitioner decide how to manage the wound?

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Jun
15

Meet the Challenges Ahead: Hyperbaric Facility Accreditation

In the late 1970s, there were fewer than 30 hyperbaric facilities operational in the United States. Most were either military, commercial or highly specialized research facilities. Today an estimated 1,350-plus facilities are in operation. Growth means change. We have seen the primary role of hyperbaric facilities transition from the treatment of diving-related disorders to providing essential primary and adjunctive treatments for multiple medical conditions. Refined research efforts will no doubt validate the continued effectiveness of HBO2 therapy, and perhaps even support new indications for treatment.

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May
04

Update your practice with these cutting-edge wound care publications

Update your practice with these cutting-edge wound care publications

These texts provide you with the most up-to-date, cutting-edge information for your wound care practice.  

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© Wound Care Education Partners. All Rights Reserved.

Nov
30

[Free Webinar] Affordable Continuing Education Solutions for Your Hyperbaric Clinic Staff

This Tuesday, December 5 at 10am EDT we are hosting a live free webinar information session to discuss affordable solutions for hyperbaric staff training in 2018.

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© Wound Care Education Partners. All Rights Reserved.

Apr
25

The interdependent nature of lymphedema and integumentary dysfunction

Even though millions are affected by various forms of lymphedema worldwide, the existing literature fails to fully define the population-based prevalence, health outcomes, and treatment costs of this disorder.

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Sep
21

Course Day Preparations

We get a lot of questions from students as to how they can prepare for their attendance at one of our live courses. Read below how to prepare. 

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Feb
07

Managing Cardiac Arrest in Hyperbaric Treatment

Cardiac arrest is a rarity in the chamber, as most arrhythmias seem to improve under hyperbaric conditions. Anecdotally, it can be noted that one patient with a myocardial infarction, who was being treated with hyperbaric oxygen as part of a research study, suffered 30 cardiac arrests during the 48 hours he was being treated with the chamber. The schedule being followed called for two hours at pressure in the chamber followed by one hour on the surface. This cycle was repeated for two days. It can be seen that the patient spent only 1/3 of his time breathing air on the surface. During the study, the patient suffered 28 cardiac arrests while breathing air on the surface, but only two arrests while at pressure in the chamber. The patient eventually recovered and returned to work. (Thurston, J. Westminster Hosp, London, Personal Communication, 1973.)

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Feb
06

Cardiovascular Issues and Management of the Critically Ill Patient in a Hyperbaric Setting: Nursing Considerations and Preventions, as described by Julio R. Garcia, RN

Cardiovascular Issues and Management of the Critically Ill Patient in a Hyperbaric Setting: Nursing Considerations and Preventions, as described by Julio R. Garcia, RN

The cardiovascular assessment of a critical care patient receiving hyperbaric oxygen therapy is similar to any cardiovascular assessment of a critical care patient. Cardiac rhythm should be assessed and monitored during the treatment. If the patient would experience a cardiac emergency during HBO treatment, the staff should be trained to handle such an emergency. It is important to remember that a patient at depth is well oxygenated and will remain so for 5 to 8 minutes. The safest way to bring a patient that has had a cardiac arrest to the surface is to bring them up at 5 psig (fastest rate on a monoplace chamber), while the staff prepares to deliver emergency care. Performing a rapid ascent using the emergency ascent button on monoplace chambers places the person at grave risk for air embolism due to expansion injuries. Once the patient has surfaced, move them to the point farthest away from the open chamber, remove the hyperoxygenated clothing, and if appropriate, defibrillate. Cold oxygen will fall to the floor and dissipate in 30 seconds, so do not place the area at an increased fire risk with the use of a defibrillator. The staff needs to be able to respond quickly and appropriately to such an emergency, so it is our recommendation that the staff be Advanced Cardiac Life Support (ACLS) certified.

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Feb
05

Cardiovascular Effects of Hyperbaric Oxygen Treatment, as described by Robert A. Warriner III, MD

Hyperbaric oxygen exposure can produce significant hemodynamic changes. An increase in systemic afterload due to hyperoxic vasoconstriction in well perfused tissues can lead to a decrease in left ventricular function and a decrease in ejection fraction in some patients. When this decrease in left ventricular function occurs in the setting of pulmonary arterial vasodilatation due to improved alveolar oxygenation with increased left atrial and left ventricular filling, acute left ventricular dysfunction and pulmonary edema can result. Cases have been reported in patients with a history of pulmonary edema or low left ventricular ejection fractions or in patients with sudden fluid shifts from volume overload. Acute pulmonary edema appears to be more common in monoplace than multiplace treatment settings, perhaps because of the requirement for patients to be in a more supine position in the monoplace chamber rather than the sitting position with legs dependent available in the multiplace chamber.

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